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Pharmacology and Administration of Cannabis

Posted by Ilo on 01/08/2018

Medical sciences have come a long way ever since the dawn of age of men. The improvement in the medical science have been a result of the increase in medical conditions that humans face and it is a bitter fact. Among these medical conditions and their treatments medical cannabis or marijuana plays a very important role in treatment and suppressing the symptoms of certain treatments that may cause discomfort to patients. It is used in nausea and vomiting caused by chemotherapy. It can also help in improving appetite in HIV patients and reduce pains.

 

 

Pharmacology

Let us discuss the pharmacology of cannabis in detail. The cannabis plant with psychoactive characteristics come in two species. Cannabis Indica and Cannabis Sativa. These two species are listed as schedule I medicinal plants. There is another species with less psychogenic properties called Cannabis Ruderalis. The cannabis plant contains around 80 cannabinoids and along with them, there are 460 other compounds. CB1 and CB2 play the main role in effects caused by the cannabinoids. These two are the primary cannabinoids and belong the group of receptors called G-Protein coupled receptors. CB1 is a receptor largely found in the brain and are thought to be responsible for psychoactive effect while CB2 is a receptor found in the body and it has the ability to reduce pain and inflammation.

 

 

Administration

Smoking is one of the most used and famous ways of in taking cannabis by the consumers. Research shows that it is the most used consumption method in USA as of 2013. This method has many other problems tailored with it that includes issues in lungs due to smoke and other cardiovascular diseases, which are common among smokers. Some other common forms of cannabis use are eating, infused into other foods, drinking and applied as oils. Another famous and common form of cannabis intake is inhalation via aerosol, which can be considered as a more viable option than smoking. Cannabis is also available in pill form like dronabinol and nabilone. There is also an oromucosal spray available, which is produced from liquid extracts formulated into the spray. The pill form intake can be potentially dangerous because it can cause a damage to liver. Any of these administration forms are not approved by the FDA because the safety of its use is not backed by proper evidence.

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